Gentamicin Injection: MedlinePlus Drug Information (2024)

pronounced as (jen ta mye' sin)

  • Why is this medication prescribed?
  • How should this medicine be used?
  • Other uses for this medicine
  • What special precautions should I follow?
  • What special dietary instructions should I follow?
  • What side effects can this medication cause?
  • In case of emergency/overdose
  • What other information should I know?
  • Brand names

IMPORTANT WARNING:

Gentamicin may cause serious kidney problems. Kidney problems may occur more often in older people or in people that are dehydrated. Tell your doctor if you have or have ever had kidney disease. If you experience any of the following symptoms, call your doctor immediately: decreased urination; swelling of the face, arms, hands, feet, ankles, or lower legs; or unusual tiredness or weakness.

Gentamicin may cause serious hearing problems. Hearing problems may occur more often in older people. Hearing loss may be permanent in some cases. Tell your doctor if you have or have ever had dizziness, vertigo, hearing loss, or ringing in the ears. If you experience any of the following symptoms, call your doctor immediately: hearing loss, roaring or ringing in the ears, or dizziness.

Gentamicin may cause nerve problems. Tell your doctor if you have or have ever had burning or tingling in the hands, arms, feet, or legs; muscle twitching or weakness; or seizures.

The risk that you will develop serious kidney, hearing, or other problems is greater if you are taking certain prescription or nonprescription medications. Tell your doctor and pharmacist if you are taking acyclovir (Zovirax, Sitavig); amphotericin (Abelcet, Ambisome, Amphotec); capreomycin (Capastat); certain cephalosporin antibiotics such as cefazolin (Ancef, Kefzol), cefixime (Suprax), or cephalexin (Keflex); cisplatin; colistin (Coly-Mycin S); cyclosporine (Gengraf, Neoral, Restasis, Sandimmune); diuretics ('water pills') such as bumetanide, ethacrynic acid (Edecrin), furosemide (Lasix), or torsemide (Demadex). other aminoglycoside antibiotics such as amikacin, kanamycin, neomycin (Neo-Fradin), paromomycin, streptomycin, and tobramycin; polymyxin B; or vancomycin (Vanocin). Your doctor may not want you to receive gentamicin injection.

Tell your doctor if you are pregnant or plan to become pregnant. If you become pregnant while using gentamicin injection, call your doctor immediately. Gentamicin may harm the fetus.

Keep all appointments with your doctor and the laboratory. Your doctor will order certain tests, including hearing tests, before and during treatment to check your body's response to gentamicin.

Gentamicin injection is used to treat certain serious infections that are caused by bacteria such as meningitis (infection of the membranes that surround the brain and spinal cord) and infections of the blood, abdomen (stomach area), lungs, skin, bones, joints, and urinary tract. Gentamicin injection is in a class of medications called aminoglycoside antibiotics. It works by killing bacteria.

Antibiotics such as gentamicin injection will not work for colds, flu, or other viral infections. Taking antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

How should this medicine be used?

Gentamicin injection comes as a liquid to be injected intravenously (into a vein) or intramuscularly (into a muscle). When gentamicin is injected intravenously, it is usually infused (injected slowly) over a period of 30 minutes to 2 hours once every 6 or 8 hours. The length of your treatment depends on the type of infection you have.

You may receive gentamicin injection in a hospital or you may administer the medication at home. If you will be receiving gentamicin injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.

You should begin to feel better during the first few days of treatment with gentamicin injection. If your symptoms do not improve or get worse, call your doctor.

Use gentamicin injection until you finish the prescription, even if you feel better. If you stop using gentamicin injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.

Other uses for this medicine

Gentamicin is also sometimes used to treat pelvic inflammatory disease, granuloma inguinale (donovanosis; a sexually transmitted disease), and other serious infections such as the plague and tularemia. Talk to your doctor about the risks of using this medication for your condition.

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What special precautions should I follow?

Before using gentamicin injection,

  • tell your doctor and pharmacist if you are allergic to gentamicin injection; other aminoglycoside antibiotics such as amikacin, kanamycin, neomycin, paromomycin, streptomycin, or tobramycin; sulfites; any other medications; or any of the ingredients in gentamicin injection. Ask your pharmacist for a list of the ingredients.
  • tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, and nutritional supplements, you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: other antibiotics such as amoxicillin (Amoxil, Larotid, Moxatag, in Augmentin, in Prevpac), ampicillin, or penicillin; dimenhydrate (Dramamine); meclizine (Bonine); or nonsteroidal anti-inflammatory drugs such as indomethacin (Indocin, Tivorbex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects. Many other medications may also interact with gentamicin, so be sure to tell your doctor about all the medications you are taking, even those that do not appear on this list.
  • tell your doctor if you are or have or have ever had cystic fibrosis (an inherited condition that affects the lungs and digestive system), problems with your muscles such as myasthenia gravis or Parkinson's disease.
  • if you are having surgery, including dental surgery, tell the doctor or dentist that you are using gentamicin injection.

What special dietary instructions should I follow?

Unless your doctor tells you otherwise, continue your normal diet.

What side effects can this medication cause?

Gentamicin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea
  • vomiting
  • diarrhea
  • decreased appetite
  • pain at the injection site
  • headache
  • fever
  • joint pain
  • unusual tiredness

Some side effects can be serious. If you experience any of these symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately or get emergency medical treatment:

  • rash
  • peeling or blistering of the skin
  • itching
  • hives
  • swelling of the eyes, face, throat, tongue, or lips
  • difficulty breathing or swallowing
  • hoarseness

Gentamicin may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

In case of emergency/overdose

In case of overdose, call the poison control helpline at 1-800-222-1222. Information is also available online at https://www.poisonhelp.org/help. If the victim has collapsed, had a seizure, has trouble breathing, or can't be awakened, immediately call emergency services at 911.

What other information should I know?

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

Brand names

  • Garamycin® I.V.

This branded product is no longer on the market. Generic alternatives may be available.

Last Revised - 12/15/2015

Browse Drugs and Medicines

Gentamicin Injection: MedlinePlus Drug Information (2024)

FAQs

Gentamicin Injection: MedlinePlus Drug Information? ›

Gentamicin injection is in a class of medications called aminoglycoside antibiotics. It works by killing bacteria.

What is the prescribing information for gentamicin injection? ›

Adults: The recommended dosage of gentamicin sulfate for patients with serious infections and normal renal function is 3 mg/kg/day, administered in three equal doses every eight hours (Table 1). For patients with life-threatening infections, dosages up to 5 mg/kg/day may be administered in three or four equal doses.

What is gentamicin drug details? ›

Gentamicin is a bactericidal aminoglycoside that was discovered and isolated from Micromonospora purpurea in 1963. It is one of the most frequently prescribed aminoglycosides due to its spectrum of activity, low cost, and availability.

Which drug should not be used with gentamicin why? ›

Avoid potent diuretics (e.g., ethacrynic acid, furosemide) because they increase the risk of ototoxicity; when administered intravenously, diuretics may enhance aminoglycoside toxicity by altering antibiotic concentrations in serum and tissue.

Is gentamicin given IM or IV injections? ›

Gentamicin is normally given by IM injection. Intravenous administration may be used for particular indications when the IM route is not appropriate The dosage is the same for either route of administration. It is desirable to measure both peak and trough serum levels during treatment.

How many days should a gentamicin injection be taken? ›

Do not use this medicine in larger or smaller amounts or for longer than recommended. Gentamicin is usually given for 7 to 10 days. Gentamicin is injected into a muscle, or into a vein through an IV. You may be shown how to use an IV at home.

What should I monitor when giving gentamicin? ›

Fluid balance should be closely monitored and dehydration must be corrected prior to commencing treatment. Blood serum levels should be measured frequently, especially in patients with renal impairment and the elderly. These should not be taken from the line being used for drug administration.

Why would a doctor prescribe gentamicin? ›

Gentamicin injection is used to treat certain serious infections that are caused by bacteria such as meningitis (infection of the membranes that surround the brain and spinal cord) and infections of the blood, abdomen (stomach area), lungs, skin, bones, joints, and urinary tract.

How is gentamicin prescribed? ›

By intravenous infusion

Initially 5–7 mg/kg, subsequent doses adjusted according to serum-gentamicin concentration, to be given in a once daily dose regimen.

What is gentamicin most commonly used for? ›

Gentamicin and other aminoglycosides are typically used in combination with a penicillin or cephalosporin for treatment of severe infections with E. coli, Staphylococcus aureus, Enterobacter, Klebsiella, Serratia, Pseudomonas aeruginosa, and other gram negative bacteria resistant to less toxic antibiotics.

What is the danger of gentamicin? ›

The risk of nerve damage is higher if gentamicin is used for longer periods of time or at higher doses. The risk is also higher in people with kidney problems. Tell your healthcare provider right away if you hear a ringing or roaring sound in your ears, feel dizzy, or have loss of hearing.

Why is gentamicin high risk? ›

This medicine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention.

What is the black box warning on gentamicin? ›

WARNINGS. As with other aminoglycosides, Gentamicin Sulfate Injection, USP is potentially nephrotoxic. The risk of nephrotoxicity is greater in patients with impaired renal function and in those who receive high dosage or prolonged therapy.

Where is the best place to inject gentamicin? ›

Proper Use

This medicine is given as a shot into a muscle or into a vein. To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days.

Why is gentamicin injection used? ›

Gentamycin Injection is an antibiotic used to prevent or treat a wide variety of bacterial infections. This may include infections of the urinary tract, bones and joints, lungs (e.g., pneumonia), brain (e.g., meningitis), sepsis, and some others.

What are the precautions for gentamicin? ›

Check with your doctor right away if you or your child have blood in the urine, change in frequency of urination or amount of urine, difficulty with breathing, drowsiness, increased thirst, loss of appetite, nausea or vomiting, swelling of feet or lower legs, or weakness.

What is the procedure code for gentamicin injection? ›

HCPCS Code for Injection, garamycin, gentamicin, up to 80 mg J1580.

Do you need a prescription for gentamicin? ›

Gentamicin is available only with your doctor's prescription. This product is available in the following dosage forms: Ointment.

What is gentamicin 20 mg injection for? ›

Gentamicin injection is used to treat serious bacterial infections in many different parts of the body. Gentamicin belongs to the class of medicines known as aminoglycoside antibiotics. It works by killing bacteria or preventing their growth.

References

Top Articles
Latest Posts
Article information

Author: Manual Maggio

Last Updated:

Views: 6668

Rating: 4.9 / 5 (49 voted)

Reviews: 88% of readers found this page helpful

Author information

Name: Manual Maggio

Birthday: 1998-01-20

Address: 359 Kelvin Stream, Lake Eldonview, MT 33517-1242

Phone: +577037762465

Job: Product Hospitality Supervisor

Hobby: Gardening, Web surfing, Video gaming, Amateur radio, Flag Football, Reading, Table tennis

Introduction: My name is Manual Maggio, I am a thankful, tender, adventurous, delightful, fantastic, proud, graceful person who loves writing and wants to share my knowledge and understanding with you.